Dissolution enhancement and physicochemical characterization of fenofibric acid in surface solid dispersion with croscarmellose sodium

Physicochemical characterization and dissolution enhancement of loratadine by solid dispersion technique

−The purpose of this investigation was to enhance the dissolution rate of loratadine using polyethylene glycol 6000 (PEG) solid dispersions (SDs). The solubility behavior of loratadine in the presence of polyethylene glycol 4000 and polyethylene glycol 6000 in water showed linear increase with increasing concentrations of PEG, indicating AL type solubility diagrams. SDs of loratadine with PEG 6...

Surface Solid Dispersion of Glimepiride for Enhancement of Dissolution Rate

Surface solid dispersions using water-insoluble carriers like crospovidone, croscarmellose sodium, sodium starch glycolate, pre-gelatinized starch, potato starch and Avicel PH 101 were investigated to enhance the dissolution rate of the glimepiride, a poorly water insoluble drug. The effect of various carriers on dissolution profile was studied using presence absence model. The surface solid di...

dissolution rate enhancement of irbesartan using solid dispersion with pegs

Issn 2347-3614 Dissolution Rate Enhancement of Ketoprofen by Surface Solid Dispersion with Colloidal Silicon Dioxide

Surface solid dispersion with insoluble carriers is considered a recently developed technique, widely applied for the enhancement of solubility and dissolution of poorly water soluble drugs. The objective of this research article is to study the effect of surface solid dispersion of ketoprofen with colloidal silicon dioxide (Aerosil 200) on the dissolution rate. Surface solid dispersion (Adsorb...

Dissolution Rate Enhancement and Physicochemical Characterization of Artemether and Lumefantrine Solid Dispersions